Could We Hack Women’s Biological Clock? A Mitochondrial Hypothesis
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Could We Hack Women’s Biological Clock? A Mitochondrial Hypothesis
mtDNA is constantly replicating during oocyte maturation, but the number is stable after maturation (metaphase II oocytes). mtDNA level in human oocytes is inversely associated with maternal age and ovarian reserve clinical indicators [5]. Mountains of evidences show that older women’s embryos have higher levels of mtDNA, which is correlated with implantation failure, and there is a threshold l...
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ژورنال
عنوان ژورنال: Global Journal of Reproductive Medicine
سال: 2018
ISSN: 2575-8594
DOI: 10.19080/gjorm.2018.03.555608